Immune Response Against Encephalitozoon cuniculi Infection
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منابع مشابه
Lack of CD4(+) T cells does not affect induction of CD8(+) T-cell immunity against Encephalitozoon cuniculi infection.
Cell-mediated immunity has been reported to play an important role in defense against Encephalitozoon cuniculi infection. Previous studies from our laboratory have underlined the importance of cytotoxic CD8(+) T lymphocytes (CTL) in survival of mice infected with E. cuniculi. In the present study, immune response against E. cuniculi infection in CD4(+) T-cell-deficient mice was evaluated. Simil...
متن کاملOptimal CD8 T-cell response against Encephalitozoon cuniculi is mediated by Toll-like receptor 4 upregulation by dendritic cells.
CD8+ T-cell immunity has been shown to play an important role in the protective immune response against Encephalitozoon cuniculi. Although earlier studies suggest that dendritic cells (DC) are important for the induction of this response, the factors responsible for initiation of the dendritic cell response against this pathogen have not been evaluated. In the current study, we demonstrate that...
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Microsporidia are obligate intracellular protozoan parasites that cause a wide variety of opportunistic infection in patients with AIDS. Because it is able to grow in vitro, Encephalitozoon cuniculi is currently the best-studied microsporidian. T cells mediate protective immunity against this parasite. Splenocytes obtained from infected mice proliferate in vitro in response to irradiated parasi...
متن کاملAltered immune responsiveness associated with Encephalitozoon cuniculi infection in rabbits.
The variation in immune response of two unrelated colonies of laboratory rabbits to high doses of heat-killed Brucella abortus strain 19 was investigated. One was a mixed-breed, multicolored colony in which a high prevalence of encephalitozoonosis had been recorded, whereas the other rabbits were derived from a colony of Dutch-marked specific-pathogen-free rabits. Although considerable variatio...
متن کاملThe immune response in a dog to Encephalitozoon cuniculi infection.
The immune response to Encephalitozoon cuniculi infection in a dog was investigated by means of the indirect fluorescent antibody test, the leucocyte migration inhibition test and the radial immunodiffusion test for serum IgG and IgM levels. Specific antibodies were detected within 7 days of infection and they persisted for 370 days. A cell-mediated immune response was detected from Day 13 foll...
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تاریخ انتشار 2001